Patrizia Vergani - Associate Professor

vergani-patrizia-dimet Department and institution: School of Medicine and Surgery, University of Milano-Bicocca
tel. +39 3315764464
Curriculum Vitae
institutional profile page: UNIMIB
see also: PubMed, BOA

Keywords: CMV-infection animal models, Down syndrome neuropeptides, fetal mesenchymal stem cells, fetal-maternal medicine

Research interests

    1) contribution of knowledge of natural history of central nervous system congenital malformations,
    2) normal anatomic variants in fetal development,
    3) etiopathogenesis of pulmonary hypoplasia in preterm rupture of membranes,
    4) reconstruction of fetal pulmonary volumes by 3D technique with a new prototype of multiplanar probe,
    5) prematurity and brain injury,
    6) vasoactive intestinal peptide for the development of CNS in Down Syndrome children,
    7) congenital cytomegalovirus (CMV) infection and related brain damage,
    8) effects of fetal mesenchymal stem cells (MSC) on prematurity-brain injury, 8) characterization of mesenchymal stem cells (MSC) derived from fetal tissues,
    9) analysis of placental growth factors related to vascular diseases during pregnancy

Internal and external collaborators

    Internal collaborations:
    Prof. Cattoretti (Dept. of Pathology), Prof. Valsecchi (Dept. of Health Sciences), Prof. Biondi (Dept. of Pediatrics), Prof. Neri (Dept. of Infantile Neuropsychiatry), Prof. Cavaletti (Dept. of Neurology).

    External collaborations:
    Yale University, New Haven, CT, USA; Leuven University, Belgium; NIH, Perinatal Branch, Bethesda, MD, USA; Texas University, Galveston, TX, USA; The Lily and Avraham Gildor Chair and The Adams Super Center for Brain Studies, Tel Aviv, Israele; Centro di Emofilia e Trombosi, Dipartimento di Medicina, Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico, Milano; Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia.

Selected pubblications

    1. Martinelli I, Ruggenenti P, Cetin I, Pardi G, Perna A, Vergani P, Acaia B, Facchinetti F, La Sala GB, Bozzo M, Rampello S, Marozio L, Diadei O, Gherardi G, Carminati S, Remuzzi G, Mannucci PM; HAPPY Study Group. Heparin in pregnant women with previous placenta-mediated pregnancy complications: a prospective, randomized, multicenter, controlled clinical trial. Blood. 2012 5;119(14):3269-75.
    2. Revello MG, Lazzarotto T, Guerra B, Spinillo A, Ferrazzi E, Kustermann A, Guaschino S, Vergani P, Todros T, Frusca T, Arossa A, Furione M, Rognoni V, Rizzo N, Gabrielli L, Klersy C, Gerna G; CHIP Study Group. A randomized trial of hyperimmune globulin to prevent congenital cytomegalovirus. N Engl J Med. 2014;370(14):1316-26.
    3. Pievani A, Scagliotti V, Russo FM, Azario I, Rambaldi B, Sacchetti B, Marzorati S, Erba E, Giudici G, Riminucci M, Biondi A, Vergani P, Serafini M. Comparative analysis of multilineage properties of mesenchymal stromal cells derived from fetal sources shows an advantage of mesenchymal stromal cells isolated from cord blood in chondrogenic differentiation potential. Cytotherapy. 2014 Jul;16(7):893-905.
    4. Oostwaard MF, Langenveld J, Schuit E, Papatsonis DN, Brown MA, Byaruhanga RN, Bhattacharya S, Campbell DM, Chappell LC, Chiaffarino F, Crippa I, Facchinetti F, Ferrazzani S, Ferrazzi E, Figueiró-Filho EA, Gaugler-Senden IP, Haavaldsen C, Lykke JA, Mbah AK, Oliveira VM, Poston L, Redman CW, Salim R, Thilaganathan B, Vergani P, Zhang J, Steegers EA, Mol BW, Ganzevoort W. Recurrence of hypertensive disorders of pregnancy: an individual patient data metaanalysis. Am J Obstet Gynecol. 2015 May;212(5):624.e1-17.
    5. Russo F, Toelen J, Eastwood M, Jimenez J, Miyague A, Vande Velde G, Dekoninck P, Himmelreich U, Vergani P, Allegaert K, Deprest J (2016). Transplacental sildenafil rescues lung abnormalities in the rabbit model of diaphragmatic hernia. THORAX, vol. 71, ISSN: 0040-6376, doi: 10.1136/thoraxjnl-2015-207949

    last update: January 2018