Pietro Genovese - Assistant Professor
Department and institution: Dana-Farber/Boston Children Cancer and Blood Disorder Centeemail: pietro.genovese@childrens.harvard.edu
tel. +1 6173205328
Biographical sketch
see also: PubMed, ORCID, Linkedin, Twitter (@Genovese_Lab)
institutional profile page: https://www.childrenshospital.org/research/researchers/g/pietro-genovese
Harvard Catalist Profiles
Publications powered by Harvard Catalyst Profiles
Keywords: Gene Editing; Gene Therapy; Hematopoietic Stem Cell; Immunotherapy; CRISPR
Research Interest - Pietro Genovese
Main topics of the group
The Genovese lab is a translational gene therapy research group that exploit a variety of cutting-edge gene editing technologies (CRISPR/Cas, TALEN, ZFN, base editors, epigenetic transcriptional regulators) to develop new therapeutic strategies for inherited and onco-hematologic diseases. They couple advanced molecular and cell biology approaches, such as viral vectors design, chimeric antigen receptors (CAR), next generation sequencing and ex vivo manipulation of stem cells and primary lymphocytes, with suitable preclinical models of disease to test novel therapeutics based on precision medicine both in vitro and in vivo.
last update: June 2020