Project Title: Characterization of disease genes causing neurodegenerative phenotypes
Project Title: Harnessing tumor microenvironment by genetic engineering
Project Title: "Mitochondrial diseases related to mtDNA in childhood: genotype-phenotype correlation and characterization of novel phenotypes"
Project Title: Study of molecular pathways involved in the pathogenesis of Fibrodysplasia Ossificans Progressiva and new therapeutic approches
Project Title: Biomarcatori in tumori solidi
Project Title: Improving outcomes in a mouse model of cardiac arrest and cardiopulmonary resuscitation
Project Title: "Pharmacological modulation of SERCA-phospholamban interaction in the heart"
Project Title: "A nanomedicine approach for theranostic of central nervous system (CNS) diseases"
Project Title: Effect of food nanoparticles on the development of celiac disease
Project Title: Identification of the targets of the Sox2 trascription factor mediating its function in the maintenance of brain cancer stem cells.
Project Title: Combinatorial strategies for dendritic cell immunotherapy in glioblastoma patients
Project Title: Characterization of the biological role of ETNK1 in atypical Chronic Myeloid Leukemia
Project Title: "Gene correction of CD4oLG gene in Tcells and HSPC for the treatment of X-linked HIGM1"
Project Title: "Prevention of Renal Injury by Nitric Oxide in Prolonged Cardiopulmonary Bypass: A Double Blind Controlled Randomized Clinical Trial in Cardiac Surgical Patients with…
Project Title: Single molecule techniques as innovative tool for nanomedicine drug design
Project Title: Studio di marcatori teranostici nel carcinoma del polmone (NSCLC)
Project Title: "Role of nuclear architecture in cell differentiation"
Project Title: "Immunotherapy by chimeric antigen receptors to target lymphoblastic leukemia"
Project Title: Finding key players in leukemia-stroma crosstalk as targets for new treatments
Project Title: Studio in vitro ed in vivo della nicchia midollare ottenuta da pazienti con leucemia linfoblastica acuta di tipo B
Project Title: Implication of cell-based mechanosensing in setting and progression of vascular pathology
Project Title: Caratterizzazione di cellule stromali mesenchimali isolate da midollo osseo di pazienti con anemia aplastica e sviluppo di un modello in vivo di nicchia…
Project Title: Risposta immunitaria alle infezioni da candida
Project Title: Role of the NFAT signaling in innate immunity
Project Title: Modelli in vitro ed effetti neuropatici dell’oxaliplatino
Project Title: Understanding pivotal mechanisms sustaining TEL/AML1+ cells through an innovative in vivo model of humanized pre-leukemic niche
Project Title: "Functional genomics in mouse models and neural stem cells in vitro: analysis of the interactions of two disease genes in the development of…
Project Title: "Proteomic analysis of urinary fractions to provide new insights into renal diseases"
Project Title: Comprehension of bone disease in mucopolysaccharidoses through the characterization of patient-derived stem cells and the study of a panel of bone remodeling markers
Project Title: Improving targeted gene editing in hematopoietic stem cells for clinical translation
Project Title: Characterization of Chimeric Antigen Receptors (CARs) as a potential tool for the treatment of haematological malignancies
Project Title: "Mass-spectrometry analysis in glomerulonephritis"
Project Title: Identification of molecular alterations associated with the progression of clear cell renal cell carcinoma by mass spectrometric approaches
Project Title: Preclinical models and therapeutic strategies fot Ventilatory Induced Dyaphragmatic Dysfunction
Project Title: Lentiviral-mediated gene transfer of TCIRG1 to correct osteoclast function in autosomal recessive osteopetrosis.
Project Title: Design, synthesis, and functionalisation of nanoparticles that cross the blood brain barrier to treat neurodegenerative disease, including Alzheimers Disease.
Project Title: Role of exosomes in pathogenesis and diagnosis of Alzheimer’s disease
Project Title: "Non-receptor tyrosine kinase Arg in clear renal cell carcinoma"
Project Title: "Exploring the potential of the hematopoietic stem cell niche using a novel in vivo model"
Project Title: Studio delle funzioni proapoptotiche di farmaci antiparassitari e del loro possibile utilizzo in vivo nel trattamento del mieloma multiplo