Project Title: Epigenetic Mechanisms in Cancer Stem Cells
Project Title: Characterization of disease genes causing neurodegenerative phenotypes
Project Title: Epigenetic role of DNA repetitive elements in skeletal myogenesis and FSHD manifestation
Project Title: MALDI-MSI in the study of glomeurlonephritis: Possible molecular indicators of CKD progression
Project Title: "Mitochondrial diseases related to mtDNA in childhood: genotype-phenotype correlation and characterization of novel phenotypes"
Project Title: Studio elettrofisiologico di mutazioni geniche coinvolte in canalopatie
Project Title: Study of molecular pathways involved in the pathogenesis of Fibrodysplasia Ossificans Progressiva and new therapeutic approches
Project Title: Ruolo dei sistemi colinergico ed ipocretinergico nella corteccia prefrontale ed implicazione in patologie legate al sonno.
Project Title: "Pharmacological Modulation of Serca-Phosphoamban Interaction in the heart”"
Project Title: "A nanomedicine approach for theranostic of central nervous system (CNS) diseases"
Project Title: Study of the transcriptomic profile of multipotent renal PKHhigh cells, isolated from human nephrospheres, for the identification of a renal stem signature and…
Project Title: Effect of food nanoparticles on the development of celiac disease
Project Title: T cell therapy in preclinical models of malignant glioma
Project Title: A retinoic acid-dependent cross-talk sustains CXCL13 expression, stromal remodeling and disease progression in a mouse model of chronic lymphocytic leukemia.
Project Title: Characterization of the biological role of ETNK1 in atypical Chronic Myeloid Leukemia
Project Title: Role of the human hematopoietic niche in inducing and supporting Myelodysplastic Syndrome and/or leukaemia evolution in Shwachman-Diamond Syndrome patients
Project Title: Study of the protective role of a combination of human genes against ischemia-reperfusion injury in in vitro and in vivo models
Project Title: "Gene correction of CD4oLG gene in Tcells and HSPC for the treatment of X-linked HIGM1"
Project Title: "Prevention of Renal Injury by Nitric Oxide in Prolonged Cardiopulmonary Bypass: A Double Blind Controlled Randomized Clinical Trial in Cardiac Surgical Patients with…
Project Title: Characterization of microRNA functional role in cholesterol metabolism and in the pathogenesis of atherosclerosis
Project Title: Studio di marcatori teranostici nel carcinoma del polmone (NSCLC)
Project Title: "Role of nuclear architecture in cell differentiation"
Project Title: Ricerca di nuove molecole solubili coinvolte nel crosstalk tra MSC e blasto di BCP-ALL
Project Title: Role of RAGE in cardiac aging
Project Title: "Immunotherapy by chimeric antigen receptors to target lymphoblastic leukemia"
Project Title: Preclinical study on the activity of L-Asparaginase in T-cell non-Hodgkin Lymphoma
Project Title: Direct neuronal reprogramming for disease modelling and cell therapy in neurodegenerative disorders
Project Title: Caratterizzazione di cellule stromali mesenchimali isolate da midollo osseo di pazienti con anemia aplastica e sviluppo di un modello in vivo di nicchia…
Project Title: Fisiopatologia delle aritmie
Project Title: Role of the NFAT signaling in innate immunity
Project Title: Modelli in vitro ed effetti neuropatici dell’oxaliplatino
Project Title: Understanding pivotal mechanisms sustaining TEL/AML1+ cells through an innovative in vivo model of humanized pre-leukemic niche
Project Title: "Functional genomics in mouse models and neural stem cells in vitro: analysis of the interactions of two disease genes in the development of…
Project Title: "Proteomic analysis of urinary fractions to provide new insights into renal diseases"
Project Title: Comprehension of bone disease in mucopolysaccharidoses through the characterization of patient-derived stem cells and the study of a panel of bone remodeling markers
Project Title: Bioinformatic and biostatistical analysis of mass spectrometric data in clinical proteomics
Project Title: Characterization of Chimeric Antigen Receptors (CARs) as a potential tool for the treatment of haematological malignancies
Project Title: "Neonatal transplantation of cord blood as a new therapeutic option for Mucopolysaccharidosis type I in the murine model"
Project Title: "Mass-spectrometry analysis in glomerulonephritis"
Project Title: Cross talk tra progenitori vascolari e sistema immunitario innato nella rigenerazione muscolare
Project Title: Indicator of growth rate and progression for the active surveillance of small renal masses by proteomic approaches
Project Title: Activation state and functionality of dendritic cells from peripheral blood of Amyotrophic lateral sclerosis patients
Project Title: Geni malattia regolati dal fattore trascrizionale Sox2 nello sviluppo del cervello
Project Title: Heredodegenerative paediatric movement disorders: phenotypes delineation and identification of new phenotypes
Project Title: Investigating KRAB/KAP1-mediated epigenetic control of differentiation and function of the adaptive immune system
Project Title: Utilizzo di recettori chimerici per la terapia delle leucemie infantili
Project Title: New protocols for in vitro differentiation of human iPSCs for disease modelling and cell therapy
Project Title: Design, synthesis, and functionalisation of nanoparticles that cross the blood brain barrier to treat neurodegenerative disease, including Alzheimers Disease.
Project Title: Role of exosomes in pathogenesis and diagnosis of Alzheimer’s disease
Project Title: Nanoparticles for the treatment of Alzheimer's Disease
Project Title: Innate immunity and tumor-stroma interactions in congenital and neoplastic cholangiopathies
Project Title: Heteromeric Nicotinic Receptors in brain development and implications for sleep-related epilepsy
Project Title: "Non-receptor tyrosine kinase Arg in clear renal cell carcinoma"
Project Title: Redox homeostasis in the multiple myeloma niche
Project Title: "Exploring the potential of the hematopoietic stem cell niche using a novel in vivo model"
Project Title: Studio delle funzioni proapoptotiche di farmaci antiparassitari e del loro possibile utilizzo in vivo nel trattamento del mieloma multiplo
Project Title: Inflammation in neurodegeneration and aging
Project Title: Wnt pathway controls DNMT3B transcription via nuclear re-localization of miR-133
Project Title: Innate immune response to microbial infection